genetics of arrhythmias
نویسندگان
چکیده
genetic basis of diffrent arrhythmias has always been an intresting subject of resesrch for scientists. here i will review in brief the most common familia arrhythmias and the new findings regarding their mode of inhetitance. this paper will mainly focus on the genetic basis of the long qt syndromes but we will also have a short review of the genetics of three other familia congenital arrhythmogenic conditions.
منابع مشابه
Genetics of cardiac arrhythmias.
Correspondence to: Dr Arthur A M Wilde, Experimental & Molecular Cardiology Group, Academic Medical Center, Amsterdam, the Netherlands; a.a.wilde@ amc.uva.nl _________________________ O ver the last decade, we have witnessed a revolution in the understanding of primary cardiac arrhythmia syndromes. These remarkable advances stemmed from the discovery of mutations, primarily in ion channel genes...
متن کامل[Genetics and arrhythmias].
In the last 50 years we have been very successful at prolonging survival and improving the quality of life of patients with cardiac disease. The innovations in technology and pharmacology, better preventive and diagnostic tools have provided tremendous breakthroughs. However, despite our best efforts, the majority of cardiac diseases are structural in origin and will progress to their ultimate ...
متن کاملThe molecular genetics of arrhythmias.
It was only ten years ago that mutations in ion channel genes were first described in patients with the long QT syndrome (LQTS) [1]. Since then, mutations in a total of eight different sarcolemmal ion channel subunit genes (KCNQ1, KCNH2, KCNE1, KCNE2, SCN5A, KCNJ2, HCN4, CACNA1C), two genes encoding sarcoplasmic reticulum (SR) Ca handling proteins (RYR2, CASQ2), and an anchoring protein gene (A...
متن کاملGenetics of Inherited Arrhythmias in Children
Over the past two decades, breakthroughs in basic science have revealed the genetic etiology for several inherited arrhythmias. Onset of arrhythmias often commences in childhood and adolescence. The aim of the article is to provide a succinct overview of the genetic background of diseases that may cause life threatening arrhythmias in children and provide a description of reported genotype-phen...
متن کاملGenetics and arrhythmias: diagnostic and prognostic applications.
This review article discusses the genetic bases of cardiac arrest with a specific focus on cardiac channelopathies and right ventricular cardiomyopathy. We review the appropriate use of genetic testing in those patients suspected to have inherited cardiac arrhythmias, highlighting the importance of most genotype-phenotype correlations for risk stratification. The article also presents the most ...
متن کاملPneumoviruses: Molecular Genetics and Reverse Genetics
Pneumoviruses are responsible for significant respiratory disease in their hosts and represent a major problemfor human and animal health. Pneumoviruses are members of the family Paramyxoviridae, subfamilyPneumovirinae and the virus particles consist of a negative-sense, nonsegmented RNA genome within a helical nucleocapsid structure enveloped in a lipid membrane derived from the ho...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
genetics in the 3rd millenniumجلد ۱، شماره ۱، صفحات ۵۲-۵۶
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023